Guanylate cyclase activity in normal and diseased human muscle.
نویسندگان
چکیده
Guanylate cyclase activity has been studied in muscle of normal subjects and of patients suffering from muscular and neuromuscular diseases. In normal tissue a guanylate cyclase activity was found in both soluble and particulate fractions of homogenate. We found also that the kinetic analysis of the enzyme of soluble differed from that of particulate fraction. A decrease of guanylate cyclase activity in crude homogenate was observed in muscular dystrophies, in neuromuscular atrophies, and in inflammatory forms of muscle disease.
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عنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 41 9 شماره
صفحات -
تاریخ انتشار 1978